Lecture 7 - Transcription Overview Template DNA Enzyme RNA...

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Transcription Transcription Overview z Template - DNA z Enzyme - RNA polymerase z Steps of transcription Prokaryotic transcription Eukaryotic transcription
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1. "Central Dogma" Central dogma, originally proposed by Francis Crick, states that the flow of the genetic information in a cell is always from DNA to RNA to protein. Although the principle of central dogma is generally correct, exceptions have been found later. e.g. retroviruses like HIV make DNA from RNA. DNA RNA Protein replication transcription translation
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2. Gene structure - A gene is the entire DNA sequences required to encode a functional polypeptide or RNA (tRNA, rRNA, miRNA etc). - Cistron is an old name for gene. -A pseudogene is DNA sequence that looks like a gene but is not transcribed, pseudogenes are most likely dead genes.
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