notes 4

notes 4 - Terms: rII mutant: produce clear plaques, cant...

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The Genetic Code 10/29/07 Overview: In class we will discuss some of the experiments that were used to reveal the nature of the genetic code and interesting features of the code. The genetic code is a three letter code, written in the ‘language’ of nucleotides. It contains 61 sense codons that specify amino acids and three nonsense or stop codons. The genetic code is degenerate, which means that there are multiple codons for some amino acids. During translation, each of the 61 sense codons is recognized by the anticodon of a tRNA. There are only about 30 different tRNAs. Some tRNAs can recognize more than one codon because unusual pairing is allowed between the third position of the codon and the corresponding position of the anticodon.
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Unformatted text preview: Terms: rII mutant: produce clear plaques, cant reproduce, only plaque: formed where T4 bacteriophage infects an Ecoli cell revertant: when rII mutates back to a wildtype after being treates with proflavin frameshift mutation: caused by addition/deletion reading frame: the codons thatre read sequentially to specify the aminoacids codon: codes for aminoacids; consists of 3 nucleotides degeneracy of the code: more than one codon codes for an aminoacid start codon: AUG (Met) on mRNA, signals the protein synthesis to start stop codon or nonsense codon: chain terminating codons wobble pairing: theres only 30 tRNAs and 61 sense codons so on the tRNA, the anticodon can wobble in the 3 rd base pair...
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This note was uploaded on 07/02/2008 for the course BIOL 202 taught by Professor Kieber-hogan during the Fall '08 term at UNC.

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