winter2008exam2

winter2008exam2 - ELEMENTARY MICROBIOLOGY PRACTICE EXAM 2...

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ELEMENTARY MICROBIOLOGY PRACTICE EXAM 2 SUMMER 2008 CORRECT ANSWERS AT END OF EXAM MATCHING: For questions 1-5, choose the definition that best matches the term. (2 points each) 1. Pathogenesis 2. Infection 3. Mortality 4. Epidemic 5. Disease Definitions for questions 1-5: a) A significant increase in cases of disease above the expected level b) A change from a state of health c) Invasion or colonization of the body by pathogenic microorganisms d) Manner, or process, by which a disease develops e) Correct definition not given MULTIPLE CHOICE. Choose the answer that best completes the statement or answers the question . (2 points each) 6. Which of the following is NOT a site in the human body where normal microbiota are found? a) Large intestine b) Brain c) Skin d) Mouth e) None of the above (All are sites where normal microbiota are found) 7. During late 2006, hundreds of people became infected with the human intestinal bacterium Escherichia coli O157:H7 by eating contaminated spinach. This is an example of: a) Vector transmission b) Parenteral transmission c) Vehicle transmission d) Aerosol transmission e) None of these 8. During the course of an infectious disease, the time when the most severe signs and symptoms of the disease occur is called the: a) Incubation period b) Period of convalescence c) Prodromal period d) Period of illness e) None of these 9. Which of the following pathogens is the LEAST virulent? a) Microbe A, LD 50 = 1,000,000 cells b) Microbe B, LD 50 = 1,000 cells c) Microbe C, LD 50 = 10 cells d) Microbe D, LD 50 = 1 cell e) Cannot be determined from information given 10. A disease that develops rapidly but lasts only a short time is said to be: a) Persistent b) Acute c) Chronic d) Latent e) None of these 11. All of the following are examples of mechanisms used by pathogens to penetrate host defenses EXCEPT: a) Enzymes b) Capsules c) Interferon d) Antigenic variation e) None of the above (all are examples of how pathogens penetrate host defenses) 12. Which of the following is NOT true of bacterial endotoxin? a) Stimulates macrophage to produce a substance (IL-1) that causes the hypothalamus to raise body temperature b) Composed of lipid A, a component of the gram-negative bacterial outer membrane c) Stimulates phagocytes to produce a substance (Tumor Necrosis Factor) that damages capillaries d) Can cause life-threatening loss of blood pressure (shock) e) None of the above (All are true of bacterial endotoxin)
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13. Which of the following is NOT true of bacterial exotoxins? a) Important in the pathogenesis of several human diseases b) Toxic effect may be against organs distant from the site of infection c) Different exotoxins may affect different types of tissues (e.g., nerves, gastrointestinal mucosa) d) They are a structural component of bacterial cells, released only when the bacterial cell dies e) None of the above (All are true of bacterial exotoxins) 14. All of the following are examples of NONSPECIFIC host defenses against pathogens EXCEPT:
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winter2008exam2 - ELEMENTARY MICROBIOLOGY PRACTICE EXAM 2...

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