Dehydration of Cyclohexanol

Dehydration of Cyclohexanol - Dehydration of Cyclohexanol A...

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    Dehydration of Cyclohexanol A Reaction of Alcohols & a Preparation of Alkenes
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    First Preparative Experiment: OH Acid Dehydrating non-nucleophilic + H 2 O Alcohol Alkene
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    What is happening? For any reaction:   Determine the nature of the  reagent.    Is it acidic, basic, nucleophilic,  electrophilic, etc.
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    What is happening? For any starting substrate, i.e. organic  starting material:   What part of the substrate is able to  interact/react with the reagent?   How is it able to interact with the reagent?
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    Dehydrative Acids: H 2 SO 4 H 3 PO 4 Alkylsulfonic acids, RSO 3 H     These acids are very good H +  sources and  their conjugate bases are not considered  nucleophilic.
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  Alcohols: R O H Only basic site (has lone e - pairs) R O H H A R O H + A H Protonated Alcohol
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This note was uploaded on 07/09/2008 for the course CHM 218 taught by Professor Loeffler during the Fall '08 term at Sam Houston State University.

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Dehydration of Cyclohexanol - Dehydration of Cyclohexanol A...

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