8.3 - Module 8 Complex Inheritance George Mellick E-mail

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Module 8 Complex Inheritance George Mellick E-mail G.Mellick@griffith.edu.au Telephone 3735 5019 (Room N44 2.11) • References – Chapter 22 of Pierce “ Genetics – A conceptual approach”
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Homework exercise Parental length (mean, mm) Offspring length (mean, mm) 30 31 35 28 33 26 32 31 29 40 33 36 31 35 27 30 34 28 38 34 The length of the middle joint of the right index finger was measured on 10 sets of parents and their adult offspring. The mean parental lengths and mean offspring lengths for each family are listed in the table. What are the descriptive statistics (i.e. mean, variance, and standard deviation) for this characteristic in the parent and offspring groups and what is the narrow sense heritability of the trait?
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Answer cov xy =112.2/9=12.5 r =12.47/3.95/3.57=0.89 b =12.47/15.57=0.80 = h 2 Plot of offspring versus parental finger joint length y = 0.8009x + 7.0128 R 2 = 0.7855 25 30 35 40 45 50 25 30 35 40 45 parental middle joint length (mm) offspring middle joint length (mm) Mean x =31.7 mm Mean y = 32.4 mm s x 2 = 15.6; s x =3.95 mm s y 2 =12.7; s y = 3.57
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Questions studied in quantitative genetics • What is the genetic and environmental contribution to the phenotype? • How many genes influence the trait? • Are the contributions of the genes equal? • How do alleles at different loci interact: additively? epistatically? • How rapid will the trait change under selection?
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Determining the contributions to phenotypic difference • There are many reasons for wanting to better understand and manipulate the contributors to phenotypic difference – can you think of some? • We first have to look at the components of
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This note was uploaded on 03/10/2008 for the course GENETICS 2007 taught by Professor Gene during the Three '07 term at Griffith.

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8.3 - Module 8 Complex Inheritance George Mellick E-mail

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