reactionflashcards - CH 310M/318M Fall 2006 Dr. Brian M....

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CH 310M/318M Fall 2006 Dr. Brian M. Bocknack Strategies for Learning Overall Transformations Reaction Flash Cards To date, we have taken a mechanistic approach towards learning organic reactions. The vast majority of the reactions we will study can be understood if we remember one simple rule nucleophiles react with electrophiles. In each step of a reaction mechanism, the best nucleophile present will typically react with the best electrophile present. If you can learn to identify what structural features make a molecule a good nucleophile, and what structural features make a molecule a good electrophile, you can predict the reaction that is most likely to occur, even if you have never seen the reactants before! Our eventual goal in this course is to apply the reactions we study towards synthesis the building up of large, structurally complex organic molecules from simple starting materials. Most of you will find a synthesis problem to be the most difficult type of problem to solve, because the development of a reasonable solution requires you to remember all of the reactions we study! Every reaction you ever learn could potentially be useful in a synthesis problem!!! In particular, you will need to know how each functional group we study is connected to other functional groups through its reactivity. Although the best way to understand why a particular reaction occurs is through detailed knowledge of the reaction mechanism, you will also find it convenient to know each reaction we discuss well enough so that you can quickly recognize the important overall transformation , without always having to write out a complete curved-arrow mechanism. In general, an organic reaction involves three things:
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This note was uploaded on 07/16/2008 for the course CH 310M taught by Professor Iverson during the Spring '05 term at University of Texas at Austin.

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reactionflashcards - CH 310M/318M Fall 2006 Dr. Brian M....

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