Drugs+for+Upper+Respiratory+(Revised) (1) - Drugs Acting on the Upper Respiratory Tract Chapter 54 Copyright 2013 Wolters Kluwer Health | Lippincott

Drugs+for+Upper+Respiratory+(Revised) (1) - Drugs Acting on...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Drugs Acting on the Upper Respiratory Tract Drugs Acting on the Upper Respiratory Tract Chapter 54
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Drugs Used to Treat Upper Respiratory Infections Drugs Used to Treat Upper Respiratory Infections Antitussives Block the cough reflex Decongestants Decrease the blood flow to the upper respiratory tract and decrease the overproduction of secretions Antihistamines Block the release or action of histamine that increases secretions and narrows airways
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Drugs Used to Treat Upper Respiratory Infections (cont.) Drugs Used to Treat Upper Respiratory Infections (cont.) Expectorants Increase productive cough to clear airways Mucolytics Increase or liquefy respiratory secretions to aid clearing of airways
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Sites of Action of Drugs Working on the Upper Respiratory Tract Sites of Action of Drugs Working on the Upper Respiratory Tract
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Antitussives Antitussives
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Antitussives (cont.) Antitussives (cont.) Caution Hypersensitivity or history of narcotic addiction Adverse Effects Drying effect on the mucous membranes CNS adverse effects GI upset
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Topical Nasal Decongestants Topical Nasal Decongestants Actions Sympathomimetic Affects sympathetic nervous system to cause vasoconstriction Causing less inflammation of the nasal membrane Indications Relieve the discomfort of nasal congestion that accompanies the common cold, sinusitis, and allergic rhinitis
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Topical Nasal Decongestants (cont.) Topical Nasal Decongestants (cont.) Pharmacokinetics Generally not absorbed systemically Any portion of these topical decongestants that is absorbed is metabolized in the liver and excreted in the urine Contraindications Lesion or erosion in the mucous membranes Caution Any condition that might be exacerbated by sympathetic activity
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Topical Nasal Decongestants (cont.) Topical Nasal Decongestants (cont.)
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