Lecture 5 10

Lecture 5 10 - Lecture 5 Nucleus Structure and Function/Nuclear Import Nucleus(of Euk cell Functions 1 Enclose cell DNA 2 Control center of gene

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Lecture 5 10/08/07 Nucleus Structure and Function/Nuclear Import Nucleus (of Euk cell) Functions 1.) Enclose cell DNA 2.) Control center of gene expression (because transcription and RNA processing) 3.) DNA Replication site Components of Nucleus 1.) Nuclear membranes (outer and inner membranes) a.k.a. nuclear envelope o outer membrane is continuous with rough ER membrane o Perinuclear Space- continuous space between inside of ER (lumen) and nucleus o inner membrane is lined with proteins called nuclear lamins to make nuclear lamina Role of lamins: make meshwork to give structure to nucleus, because the nucleus can be big (up to 1/5 of volume of cell) and it needs its own cytoskeleton to give structure Anchor DNA to envelope Diseases associated with nuclear lamina: LAMINOPATHIES -causes muscular dystrophy 2.) DNA – 2 forms o Euchromatic open form, can be actively transcribed o Heterochromatic closed form, cannot be transcribed o Packaged around histones (major structural protein of chromosomes)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 07/21/2008 for the course BICD 110 taught by Professor Mel during the Fall '06 term at UCSD.

Page1 / 2

Lecture 5 10 - Lecture 5 Nucleus Structure and Function/Nuclear Import Nucleus(of Euk cell Functions 1 Enclose cell DNA 2 Control center of gene

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online