Lecture 17 11

Lecture 17 11 - Lecture 17 11/19/07 – Cytoskeleton: Actin...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Lecture 17 11/19/07 – Cytoskeleton: Actin continued and Myosin Toxins produced by plants, fungi, sponges target filament polymerization and act as defense against predation. • Provides protection for those that can’t get up and move away • These toxins affect actin cytoskeleton • Toxins are used in cell biology labs to help study cytoskeleton Proteins produced that affect cytoskeleton 1.) Cytochalasin – made by fungi, makes a cap at (+) end -promotes depolymerization at (-) end 2.) Phalloidin – made by fungi: deathcap mushroom-causes stabilization of filament, absolutely no depolymerization, continue to make actin filament but none will be destabilized-does this by inhibiting ATP hydrolysis-very toxic, if you ingest you will die 3.) Latrunculin – made by sea sponge-binds actin monomers and prevents polymerization-increases depolymerization 4.) Swinholide – sea sponge-severs actin filaments-sequesters actin dimers-acts similarly to latrunculin Organisms that use cytoskeleton to their advantage...
View Full Document

This note was uploaded on 07/21/2008 for the course BICD 110 taught by Professor Mel during the Fall '06 term at UCSD.

Page1 / 2

Lecture 17 11 - Lecture 17 11/19/07 – Cytoskeleton: Actin...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online