Lecture 7 Cardiac Biomechanics

Lecture 7 Cardiac Biomechanics - Lecture 7 Cardiac...

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Lecture 7 Cardiac Biomechanics I. A strip of cardiac muscle A. Passive Tension B. Active tension C. Total Tension D. Different preloads (stretch) As you increase preload, increase shortening If preload increases, afterload decreases because total load is the same T.L. = P.L. + A.L. E. Different afterloads – constant preload Decrease amount of shortening but increase amount of tension F. Inotropic state (hormones, etc, can change this in cardiac muscle) (+) inotropic agent (+) inotropy increase contractility (-) inotropy decrease contractility
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II. Intact Heart A. Passive tension B. Active tension III. Pumping Heart – blood flows from areas of higher pressure to areas of lower pressure A. LV Anatomy/Function Contraction increases pressure Relaxation decreases pressure Diastole – ventricular relaxation Low ventricular pressure Mitral valve open Blood fills LV Systole – ventricular contraction LV builds pressure P LV > P LA mitral valve close, eject blood Preload
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