Lecture 12 Kidney

Lecture 12 Kidney - Lecture 12 Kidney Kidney get rid of...

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Lecture 12 Kidney Kidney – get rid of water soluble wastes but keep what you need I. Anatomy Cortex and medulla: make urine Drains and collects in pelvis Nephron – functional element for making urine 2 parts: tubular system and blood supply system A. Tubule system B. Blood supply II. Urine formation – get rid of water soluble waste A. At glomerulus Basic Filtration: solution filtered out of blood and into Bowman’s space area Different from other capillary beds because: 1.) high Pc (arterioles surround capillary bed) 2.) high K – easy for stuff to get filtered from blood to Bowman’s space because in cap walls are a bunch of pores big enough to let stuff through water passes easily small solutes (salts, glucose, urea) passes easily large solutes (proteins) pass poorly, depends on type of proteins (e.g. albumin is too big) RBC’s don’t pass at all
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3.) Glomerular filtration rate – how much water is filtered out into Bowman’s space Add up all nephrons: GFR ~125 mL/min
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This note was uploaded on 07/21/2008 for the course BIPN 105 taught by Professor Armour during the Winter '08 term at UCSD.

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Lecture 12 Kidney - Lecture 12 Kidney Kidney get rid of...

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