Lecture 12

Lecture 12 - Lecture #13 Tuesday 5/13/08 -1- Announcements:...

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Lecture #13 – Tuesday 5/13/08 - 1 - Announcements: - Midterm Scores . Official scores are posted: nowhere. But you can email me ( tliu@ucsd.edu ) if you want to know your score. o Scantrons . Scantrons were passed back in class on Tuesday. If you didn’t pick up your scantron but would like to have it, you can pick it up from Dr. Johnson’s project assistant, Alison Gerrity, NSB 4119. o Regrades . If you didn’t do as well on the midterm as you had hoped, you have some options: 1. Request a regrade – but realize there are xeroxed copies of your scantron. 2. Study harder for the final – remember if you do really well on your final, we will throw out your midterm score. NOTE : CAPE evaluations were taken at the beginning of class. It took about ~20 minutes, so there’s a pause in the PODCAST. This lecture was based off slides (to be posted on the WebCT) that are not figures from the book. It’d be helpful to have the slides available while using these notes. NOTE: I use a lot of abbreviations in the notes (because it’s easier for me to do so), but be careful about using them on the test. To be safe for the final, don’t use abbreviations. Example: For the notes: Breast Cancer = BC. For the test: Breast Cancer = Breast Cancer BREAST CANCER Epidemiology, Therapeutics/Clinical practice, Research Models and Approaches Johnson has taken Significant Factors related to Breast Cancer (BC) - Female o Although men can also develop breast cancer, in general being a female does increase your risk. - Age o It is pretty common by age 75, 1 in 9; rare at 25 yrs. o Overall approx. 1 in 8 women will be affected in their lifetime and can be quite common. In some families more common than that. o Medium age of diagnosis: 60-65. Primarily affects older women, although it is not impossible for women even under age of 30 to develop cancer. Incidence rate increases as you approach menopause. Incidence vs. Mortality Rates: - Incidence rates of breast cancer have increased, but mortality rates have remained the same. o Increased rate of breast cancer occurrence due to better detection methods (better mammograms). Increased level of screening particularly in older female populations. Mammograms and self examination. o Increased life span of female population o Increased age to first child birth
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Lecture #13 – Tuesday 5/13/08 - 2 - o Increased smoking in female population in this time frame as women get past a certain age o Mortality rate drop: increased efficacy of treatment. In particular, a number of different treatments that focus on decreasing hormone availability or changing the way breast cancers respond to hormones, hormones important for their growth and expansion. (Hormonal inhibitors) Breast cancer statistics - Most common type of cancer in human beings worldwide: UV induced skin cancer. o
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Lecture 12 - Lecture #13 Tuesday 5/13/08 -1- Announcements:...

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