w07BbMemCells - Biological Membranes FluidMosaic Model I...

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Biological Membranes: Fluid- Mosaic Model I. Characteristics: A. Fluid: unsaturated H–C tails of phospholipid and cholesterol molecules keep membrane fluid at normal body temperature; phospholipid bilayer forms spontaneously in aqueous solution
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Biological Membranes: Fluid- Mosaic Model I. B. Mosaic: proteins embedded in bilayer 1. Determine function of membrane 2. Each membrane type has its own special protein gang
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Biological Membranes: Fluid- Mosaic Model I. B. 3. Integral proteins = transmembrane proteins: span the bilayer
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Biological Membranes: Fluid- Mosaic Model I. B. 4. Peripheral proteins = cell surface proteins: attached either to the “outside” or “inside” of the bilayer
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Biological Membranes: Fluid- Mosaic Model I. C. Selective permeability 1. Some stuff can enter the cells easily, some stuff can’t a. Hydrophobic tails impede hydrophilic substances
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Biological Membranes: Fluid- Mosaic Model I. C. 1. b. Small, slightly polar molecules (H 2 O, for example) can diffuse c. Large macromolecules and ions need help getting across
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Biological Membranes: Fluid- Mosaic Model I. D. Methods for getting across = transport 1. Passive: no energy needed, things move along their concentration gradient
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Biological Membranes: Fluid- Mosaic Model I. D. 1. a. Diffusion: concentration gradient b. Osmosis: diffusion of H 2 O only
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