HW4 - Jim Watson J. Craig Venter Celera Sanger sequencing...

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Chem 476 HW 4 Due Sept 19, 2007 “Venter DNA” Name:________________________ Please complete all questions. Do your work on additional sheets of paper and staple to the back of this sheet. Do not put your answers on this page. You may work with your classmates on this and all homework assignments. I will grade the same three questions for all students and post the answers to the questions after they are due. I.) Problems from the textbook and supplement (do not hand in). Answers are in the textbook (short answers) and supplement (full answers to text AND supplement), but work through on your own first. : Text: 4.1-15 (many of these are short answer) Supp: 4.1, 2, 5, 7, 11, 12, 14, 18, 20, 21, 22, 24, 26, 28, 32. II.) Additional Problems to hand in : Paper: New York Times, Tuesday September 4, 2007. “In the Genome Race, The Sequel is Personal” (see course website for link) Define these terms: (Feel free to use other resources but provide your sources and any url used.)
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Unformatted text preview: Jim Watson J. Craig Venter Celera Sanger sequencing 454 sequencing General Questions 1.) Why is it hard to get DNA sequence at the tips and center of a chromosome? 2.) What is a diploid genome? (Use one of the Graphic links to help answer.) 3.) In what ways does genetic variation between individuals come about? Discuss at least three types of variation and give typical numbers of each type. 4.) How similar is the genome between two people likely to be? Is this number surprising? 5.) What are some of the possible benefits of knowing a persons genome? What are some of the possible ethical issues? Would you want your genome sequenced? Why or Why not? 6.) Can Venter drink milk? Is he predisposed to a heart attack? What kind of earwax does he have? (Hah!) Give the genetic basis for your answer. Is the answer always a simple one? Why or why not? (Use one of the Graphic link to help answer)....
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