Q4a - RNA is susceptible to hydrolysis b Which is more...

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Chem 476 September 21, 2007 Quiz 4 Name:________________________ Please complete all questions. You have 10 minutes for the quiz. 1.) (30) The composition of one strand of double-helical DNA(in mole-fraction units) is [C]=0.24, [T] =0.33. a.) What can you say about the [A] and [G] for the same strand? [A]+[G]=1-(0.24+0.33)=0.43 b.) What can you say about the [A], [G], [C], and [T] for the other strand? [G]=0.24, [A]=0.33, [C]+[T]=0.43 2.) (30) a)Which is more stable at high pH, RNA or DNA ? Explain briefly.
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Unformatted text preview: RNA is susceptible to hydrolysis b) Which is more stable at low pH, RNA or DNA? Explain briefly. DNA is susceptible to depurination. 3.) (40) Do you expect Chargaff’s rules to be followed for the following cases. Explain briefly. a.) The mRNA for the PKR gene No. It’s single-stranded. b.) Reovirus, which has a dsRNA genome Yes. It’s double-stranded. c.) RNA-DNA hybrid during reverse transcription of the HIV genome. Yes. It’s double-stranded. d.) ssDNA virus Φ X175 No. It’s single-stranded....
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