Lecture11 copy

Lecture11 copy - Lecture #11 (Vertebrate kidneys) I. the...

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Lecture #11 (Vertebrate kidneys) 21/07/2008 12:05:00 I. the excretory system A. Excretory organs 1. Liver: hydrophobic and large wastes, urea o where urea is made!! 2. colon: processes wastes, excretes excess ions 3. kidney: o hydrophobic wastes o osmotic balance o blood pressure regulation o pH regulation B. Urinary system (overview) (figure 1) II. the kidney A. functions 1. ion balance o especially Na+ and K+ 2. osmotic balance  determines volume (and concentration) of urine produced 3. Blood pressure o Control blood volume  o also ECF volume
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o hormone interactions 4. pH balance o retains/excretes H+ or HCO3- 5. excretion o nitrogen excretion o urea o hydrophilic wastes 6. endocrine function (hormones) o rennin BP regulation o erythropoietin  regulation of RBC synthesis (figure 2) B. Nephron Structure and function (figure 3) 1. filtration= move fluid (plasma) across capillary membranes by pressure (BP) o occurs in Bowman’s capsule!!! 2. reabsorption= from filtrate to body (blood)  o 99% of original volume is retained o always: glucose, amino acids, water o regulated:ions, water 3. secretion= body to filtrate o creatinine o regulated: ions
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1.) Proximal Convoluted Tubule (PCT):  most reabsorption and secretion take back as much as possible all your glucose, most H2O 2.) Loop of Henle establishes concentration gradient in medulla Descending Limb:     o permeable to H2O, but not salt Ascending Limb     : o permeable to salt, but not H2O *counter current multiplier!
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This note was uploaded on 07/23/2008 for the course BIO 131 taught by Professor Mostman during the Summer '08 term at UCSC.

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Lecture11 copy - Lecture #11 (Vertebrate kidneys) I. the...

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