Lh5Ch14GlycolPPP

Lh5Ch14GlycolPPP - Chapter 14 Glycolysis, Gluconeogenesis...

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Glycolysis Gluconeogenesis and the Chapter 14 Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway Some Discoverers of Glycolysis
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Showed that the sugar intermediates were Phosphorylated
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Hexokinase
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Phosphohexose Isomerase Isomerase involved Ring Opening and Closing Phosphofructokinase-1 (PFK-1)
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Fructose-1,6-bisphosphate Aldolase Keep Track of those Carbons!
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TIM 3-P-Gyld DH
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3-P-Gyld Mechanism 3-PGA Kinase 3-PGA Mutase
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Enolase is a Dehydrase Pyruvate Kinase
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Previous Homework Problem Add up all the G’ o ‘s and see how: 1. Aldolase’s endergonic G is over come. 2. Total for Glycolysis…what enzymes are doing the work? Homework Problem – Thermodynamics of Glycolysis Hexokinase -16.2 kJ/mole Isomerase 1.7 PFK-1 -14.2 Aldolase 23.8 TIM 7.5 First Half = +2.1 kJ/mole 3-P-Gyld DH 6.3 PGA Kinase -18.5 Mutase 4.4 Enolase 7.5 Pyr Kinase -31.4 Second Half = -31.7 kJ/mole Overall = -29.6 kJ/mole The REAL G
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Showed cancer cells had high rate of glycolysis, first to crsytalize most
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This note was uploaded on 07/24/2008 for the course BCH 3033 taught by Professor Makemson during the Summer '08 term at FIU.

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Lh5Ch14GlycolPPP - Chapter 14 Glycolysis, Gluconeogenesis...

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