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BMB 526 M OLECULAR B IOLOGY AND G ENETICS Fall, 2006 Course Faculty John L. Wang (course coordinator) Office: 402C Biochemistry Building. Tel: 353-9542 E-mail: [email protected] Andrea Amalfitano Office: 4194 Biomedical & Physical Sciences Building. Tel: 355-6463 (ext: 1537) E-mail: [email protected] Rebecca MacFalda Office: B240 Life Sciences. Tel: 355-1297 E-mail: [email protected] Carol Wilkins Office: 116B Biochemistry Building. Tel: 353-4927 E-mail: [email protected] Course Objectives The general objective of this course is to instruct students in the basic concepts, principles, and language of molecular biology and human genetics and to equip students to analyze diseases and the responses to diseases in molecular and genetic terms. These principles will be illustrated using examples from clinical practice. We anticipate that this training will enable students to recognize and solve genetic problems encountered in subsequent clinical training and experience. Specific educational objectives for various sections of this course are included in the body of the coursepack. These objectives represent a subset of the core competencies in genetics that are expected of all health professionals, as put forth in guidelines from the American Society for Human Genetics and the National Coalition for Health Professional Education in Genetics. Prerequisites This course assumes no prior experience or instruction in molecular biology and genetics beyond elementary college biology. Mastery of concepts introduced in prior first-year medical school courses (e.g., BMB514) will be expected. Course Credit by Waiver Examination For students with strong prior instruction or experience in molecular biology and human genetics, a waiver examination will be offered on Sunday, August 27, 2006 from 3:00 to 5:00 p.m. in Room E-105, Fee Hall. The examination may comprise multiple choice, short answer, and essay questions. The pass level for this waiver exam will be 75% for all students (CHM and COM). In accordance with college policies (July 1996), students may take the waiver exam only once for any specified course. Moreover, students who have taken but not passed the remediation exam for BMB526 will not be eligible to take a subsequent waiver exam. i
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Textbooks Students are expected to acquire and use both a textbook of biochemistry and molecular biology and a textbook of medical genetics. For molecular biology, the required textbook for Fall 2006 will be Lippincott’s Illustrated Reviews: Biochemistry , 3 rd edition, by Champe, Harvey, and Ferrier (Lippincott Williams & Wilkins, 2005). The Lippincott book, also required for BMB514, covers the molecular biology content of this course adequately but without much depth. Students who want more thorough explanations of concepts should consult any of the more substantive undergraduate biochemistry texts (Lehninger, Stryer, Marks, Devlin, Meisenberg & Simmons, or Voet & Voet). The required genetics textbook for Fall 2006 will be Medical Genetics
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This note was uploaded on 07/25/2008 for the course BMB 526 taught by Professor Wang during the Fall '06 term at Michigan State University.

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