BMB526FS2007Exam1Form1AR

BMB526FS2007Exam1Form1AR - Form 1A-1 BMB 526 Exam 1...

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Form 1A-1 BMB 526 Exam 1 November 5, 2007 You may use this grid to record your answers for comparison with the posted answer keys. Version of the Exam: 1A 1. _____ 8. _____ 15. _____ 22. _____ 29. _____ 2. _____ 9. _____ 16. _____ 23. _____ 30. _____ 3. _____ 10. _____ 17. _____ 24. _____ 31. _____ 4. _____ 11. _____ 18. _____ 25. _____ 32. _____ 5. _____ 12. _____ 19. _____ 26. _____ 33. _____ 6. _____ 13. _____ 20. _____ 27. _____ 34. _____ 7. _____ 14. _____ 21. _____ 28. _____ ------------- The information provided below may be useful in answering some questions. INFORMATION ON COMPONENTS OF RIBOSOMES I. Prokaryotes (e.g. E. coli ) RIBOSOME (70S) Large Subunit (50S) --- 5S and 23S rRNAs + many proteins Small Subunit (30S) --- 16S rRNA + many proteins II. Eukaryotes (e.g. human) RIBOSOME (80S) Large Subunit (60S) --- 5S, 5.8S, and 28S rRNAs + many proteins Small Subunit (40S) --- 18S rRNA + many proteins
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Form 1A-2 BMB 526 Exam 1 - November 5, 2007 NAME (print clearly) ___________________________________ CHM COM (circle one) BEFORE you begin the exam, please complete the following information on your response sheet: (a) your name and signature (b) your student number (PID) (c) your college --- in the area under SECTION: mark 001 for CHM student mark 002 for COM student (d) your version of the exam is 1A --- mark this in the area under FORM This exam contains 34 questions. For each question, please mark the letter on the response sheet that corresponds to the best available answer. When you leave the exam room, please turn in your RESPONSE SHEET and your EXAM to the proctors. Once you exit the exam room, please DO NOT re-enter until the end of the exam period. To reduce the noise entering the exam room, please do not remain in the hall outside the exam room. Answer Keys will be posted at the Angel website following the exam. You have 65 minutes to complete this exam. Do well and good luck.
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Form 1A-3 Questions 1 and 2 refer to the clinical problem below. Two patients are diagnosed with problems in the pathway for the degradation of phenylalanine. The first patient has a defective phenylalanine hydroxylase enzyme resulting in the disease phenylketonuria (PKU). The second patient has a defective homogentisate oxidase enzyme resulting in the disease alcaptonuria. 1. Since both patients cannot completely degrade phenylalanine as a result of two different defective enzymes, this would be considered an example of: A. allelic heterogeneity B. phenocopies C. locus heterogeneity D. syntenic genes E. homologous recombination 2. For both patients, identify the “major class of mutation” and the type of inheritance pattern you would expect for these two defective enzymes. A. Gain of function mutation, dominant inheritance B. Loss of function mutation, dominant inheritance C. Gain of function mutation, recessive inheritance D. Loss of function mutation, recessive inheritance 3. Which of the following statements regarding DNA secondary structure is correct? A. It consists of two DNA strands in a parallel arrangement. B. It consists of duplex DNA wrapped around histones and coiled into solenoids. C. It consists of two duplex DNA molecules wrapped around histones.
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This note was uploaded on 07/25/2008 for the course BMB 526 taught by Professor Wang during the Fall '06 term at Michigan State University.

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BMB526FS2007Exam1Form1AR - Form 1A-1 BMB 526 Exam 1...

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