Mechanism of Infectious Disease

Mechanism of Infectious Disease - Mechanism of Infectous...

Info icon This preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Mechanism of Infectious Disease. Mechanism of Infectious Disease. Name of the student: Student identification number: Course tittle: Course code: Submitted to: Date of submission: 1
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Mechanism of Infectious Disease. Mechanism of Infectious Disease CASE STUDY. 32 yr. old general labor fell ill shortly after working on a job digging up old water pipes. He worked around shallow pools of stagnant water. 10 days after the contract ended he developed fever and aching muscles. He also had nausea, vomiting, and diarrhea. He went to the doctor, after hearing the man's story the doctor suspected West Nile fever and ordered serological testing. The man went home to recover, feeling better by the end of the week. 2
Image of page 2
Mechanism of Infectious Disease. 1. The doctor ordered serological testing. How would antibody titers assist the doctor in confirming the diagnosis? The measure of antibody titers helps to determine the immune response posed by the body against the virus. Laboratory diagnostic test for West Nile virus involves the testing of the serum or the cerebrospinal fluid antibody titers to detect West Nile virus specific IgM antibodies (McCance and Huether, 2015) . The IgM antibodies usually are detected by around 3-8 days after the infection and would persist for about 30-90 days post infection (CDC, 2015). Therefore, the presence of IgM antibodies can represent a past infection. After some times, IgG antibodies are produced that would persist for many years following symptomatic or asymptomatic infection. Hence in this case, the presence of IgG antibodies alone is a sign of a past infection and the body has developed immunity against it (CDC, 2015). Therefore, the antibody titers of anti-West Nile virus IgM or IgG will assist the doctor to determine if the infection is a recent infection or a past infection which the body has already developed immunity against. Rising antibody titers indicate an active infection and hence need for further evaluation and treatment. This is because as the virus continues to replicate in the body, the body tries to launch an immune response by producing more and more antibodies to fight the infection hence the rising titers.
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern