E. History of microbiology1. Robert Hooke (1635-1703) -rich businessman-examined the structure of cork; suggested that all living creatures were made of individual cells. -coined “cells”2. Anton van Leeuwenhoek (1632-1723) -Was the first to describe and observe bacteria.-Developed the solar microscope with high resolving power.-the first bacterium was recorded in 1683 (which was 200 years before “spontaneous generation” was disproved and the “germ theory” of disease was accepted)3. Louis Pasteur (1822-1895) -1862 published a report examining the doctrine of “spont. generation”. -chemist; his approach was influence by chemical training--MAJOR contribution:1. Disapproved spont, generation theory.Redi, Spallanzani, Schulze, Cagniard-Latour, Schwann, and Kützing also did experiments that disproved spont gen.2. Heat sterilizationAutoclave (developed with Chamberland)- sterilizes using superheat system.Pasteurization-low heat (50-55C) to kill bacterial pathogens in wine 3. He was the first to us terms “aerobe” and “anaerobes”
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