Lecture 16: Karyotyping When Karyotypes are prepared, ___white____ blood cells are usually collected fixed and stained. To get a lot of cells in Mitosis, the cells are stimulated with growth factors _____ to divide. Then the cells are arrested with colchicine a drug that blocks _microtubule depolymerization___. The homologous chromosome pairs are lined up by _size__ and banding pattern (centromere position) Banding is due to differential binding of the stain to the _proteins____ associated with the chromosome. Meiosis Meiosis is the process whereby _gametes___ are formed. This requires division of homologous chromosome pairs______ in germline cells. If meiosis is normal in mammals, this causes the cells to be (choose 1: diploid _haploid or polyploid).In Interphase of Meiosis Ithe chromosomes duplicate to form __sister chromatids__________. In Prophase I of Meiosis __homologous___ chromosomes are condensed into the_synaptonemal___ complex, form a tetrad___ and crossing over__ occurs at the chiasmata.In Metaphase I of Meiosis the spindle __microtubules__
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