Lectures 17, 18 and 19 are on Mendel and the gene idea. Chapters 14 and 15 What is a character? What is a trait? What is an allele? What is a hybrid? What is true breeding? What is the Law of segregation? What is the Law of Independent assortment? What does "particulate" inheritance mean? Homologous chromosomes carry two ________________ for a trait at the same ___________ How do you determine probabilities? When do you use the Multiplication rule? When do you use the Addition rule? Not all gene alleles are completely dominant or recessive. Incomplete Dominance example Snapdragons have 2 alleles for either red or white flowers. Homozygotes are red or white, hetreozygotes are ________________. The genotype and phenotype will have ________________ratios. Give 2 human disease examples. Co-dominance example blood types, MM, NN or MN. More than 2 alleles, AA, Ai, BB, Bi, AB, ii, and A and B are dominant to I, gives 6 blood types for this trait. Pleiotropy Give an example from class: Example from last year: name several defects that would be caused by defective dynein motors Mutations in the globin gene affect O2 binding by hemoglobin This causes RBCs to sickle when O2 is low and can cause capillaries to plug and pleiotrophic effects because of this. Name 4 pleiotropic effects Define Epistasis Give 1 example The dihybrid cross ratios will be:
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