final key - MCB 11 Final Examination Key 1. a. Spring 2006...

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MCB 11 Spring 2006 Final Examination Key 1. a. (10 pts) Why is the presence of active enzyme so important to whether or not a molecule is made or degraded in an organism? Molecules are made through a sequence of chemical reactions (pathway). None of these reactions will progress fast enough to be useful unless there is a catalyst present to speed it up Enzymes are the biological catalysts. b. (5 pts) In what structure (not molecule) in the cell would you find the information that tells it how to make a specific enzyme? chromosomes c. (5 pts) What molecule found in that structure (see b) actually carries that information? DNA d. (6 pts) Draw a schematic view of that molecule (see c) and circle the part that actually carries the information. Show double helix: 2 strands wrapped around each other. Each strand has the backbone …. P-S-P-S-P …. with one of the four bases, A,T,G,C hanging off each sugar. The 2 strands are linked with dotted hydrogen bonds so that only A …. T and G …. C pairs are formed. The A,T,G,C of one (not both) of the strands are circled. e. (5 pts) We must do two things with this information. We must make copies of it so that future generations can have it, and we must use it to direct the synthesis of enzymes. What is the name of the process of making an exact copy? replication f. (5 pts) What is the name of the first step in the process (see e) by which it is used to direct enzyme synthesis? transcription g. (15 pts) Name two substantive ways in which the two processes (see e) or products of those processes are the same and three in which they are different. Both involve base pairing A …. T and G …. C . Both require opening up the double helix. Transcrption makes a single strand, replication makes a double strand. Transcription makes a product that has ribose, replication makes a product that has
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deoxyribose. Transcription makes a product that uses the base U, replication makes a product that uses the base T. h. (10 pts) For many years, the most puzzling question about the process of enzyme synthesis was that there was no clear mechanism by which the molecular structure of the information could be physically read so that the individual amino acids in solution can be put into correct position. What is the single key primary feature of the process that performs this function? Explain. The use of transfer RNA (tRNA). One one side, it has the anticodon which reads the codon on the mRNA that carries the information identifying the next amino acid to be added to the growing protein. On the other side, it binds the amino acid that is called for by that codon. i. (5 pts) What geometric shape does the protein take initially as it is synthesized? Explain briefly. Just as it is made, it takes the form of a linear chain of amino acids
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This note was uploaded on 08/01/2008 for the course MCB 11 taught by Professor Alper during the Spring '06 term at University of California, Berkeley.

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final key - MCB 11 Final Examination Key 1. a. Spring 2006...

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