MCB 11 February 17, 2006 Spring 2006 Problem Set 2 M. D. Alper 1. What characteristic of oxygen leads to the capability of water to dissolve charged and ionic materials? Discuss in terms of energy considerations and the various aspects of those considerations. 2. Excess doses of Vitamin E lead to its accumulation in the body while excess doses of Vitamin C generally do not. Explain. 3. The acid group --COOH usually takes another form in water. a. What is that form. b. How is the H different in these two forms? Discuss in terms of its electronic structure. 4. Liposomes (vesicles) can be used as carriers of polar drugs in the body. Micelles are also being studied for the purpose of carrying nonpolar drugs in the body. a. What is a non polar molecule? b. Describe what happens when non polar molecules are put into a container of water. Why does this happen? Explain fully. c. Draw a diagram of a micelle, showing where the non polar drug would be carried. Explain why you put it where you did.
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Chemical polarity, non polar molecules, non polar molecule, M. D. Alper