berg_8e_testbank_chapter36[1] - Chapter 36 Drug Development...

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Introduction to General, Organic and Biochemistry
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Chapter 15 / Exercise 15-9
Introduction to General, Organic and Biochemistry
Brown
Expert Verified
Chapter 36 Drug DevelopmentMultiple-Choice Questions1)What concentration of a drug gives 90% of the maximum response?A)DC90B)EC90C)LC90D)MC90E)RC90Answer: B
Section: 36.12)What compound is increased by the action of Sildenafil (Viagra®)?
Section: 36.23)What set of “rules” gives a general indication of the bioavailability of a drug?
Section: 36.1
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The document you are viewing contains questions related to this textbook.
Introduction to General, Organic and Biochemistry
The document you are viewing contains questions related to this textbook.
Chapter 15 / Exercise 15-9
Introduction to General, Organic and Biochemistry
Brown
Expert Verified
4)What term describes a molecule that binds to a target molecule?
Section: 36.15)Which of the following is conjugated to drugs to aid excretion?A)glucuronic acidB)cholic acidC)glutamic acidD)ascorbic acidE)None of the answers is correct.Answer: A
Section: 36.16)Which of the following enzymes is associated with the inflammatory response?
Section: 36.27)Who is credited with the discovery of penicillin?
Section: 36.28)What method, employed in combinatorial chemistry, begins by dividing the starting scaffold into a number of sets?
Section: 36.29)Which of the following class of drugs is a common treatment for hypertension?A)beta blockerB)statinsC)protease inhibitorsD)phosphodiesterase inhibitorsE)None of the answers is correct.Answer: A
Section: 36.310)In which phase of drug development do healthy volunteers take the drug for initial safety studies?
E)None of the answers is correct.Answer: ASection: 36.4Fill-in-the-Blank Questions11.Kdcorresponds to the concentration of ligand, at which ______________ (fraction?) of the receptors are bound to ligand.
Section: 36.112. ________________ is the science that deals with the discovery, chemistry, composition, identification, biological and physiological effects, uses, and manufacture of drugs.
Section: Introduction13. A drug’s concentration at its target site is affected by its ADME, which is an acronym thatstands for _________________________________.
Section: 36.1

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