Transcription - JACS 124 , 13795 (2002) Vitamin D...

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RNA Polymerase as a Drug Target FDA-approved antibiotic from Streptomyces Binds more tightly to prokaryotic RNA polymerases Rifamycin S Kishi: Tetrahedron 37 , 3873 (1981) S R 2 O Me Me R 4 O Me R 3 O Me R 1 O S NHC O Me O O O OAc Me Me OH Me OH Me MeO Me OH O O Me
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Hormone-Dependent Transcription
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Vitamin D Receptor•1,25(OH) 2 D 3 wild-type receptor (X-ray crystallography) R274L receptor (model) Koh:
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Unformatted text preview: JACS 124 , 13795 (2002) Vitamin D ReceptorAgonist agonist (model) agonist and 1,25(OH) 2 D 3 superposition (model) Binding of 3 Agonists to R274L Variant (model) Phylogenetics based on r RNA Sequences Formation of Earth: 5B years ago Origin of Life: 4B years ago Woese: Curr. Biol. 6 , 1060 (1996)...
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Transcription - JACS 124 , 13795 (2002) Vitamin D...

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