NURS 6521N-30: Advanced Pharmacology WEEK 10 INITIAL POST Hormone Replacement Therapy Hormone replacement therapy (HRT) has become another controversial issue. HRT has risks and benefits and when prescribing HRT, advanced practice nurses must weigh the strengths and limitations of the prescribed supplemental hormones. If advanced practice nurses determine that the limitations outweigh the strengths, then they might suggest alternative treatment options such as herbs or other natural remedies, changes in diet, and increase in exercise (Arcangelo and Peterson, 2013). The following discussion will describe the strengths and limitations of HRT, explain why and advanced practice nurse would or would not support hormone replacement therapy, and explain whether to prescribe supplemental hormones or recommend alternative treatments to patients with hormone deficiencies. Benefits and Limitations of HRT HRT is commonly prescribed for the treatment of symptoms associated with menopause due to decline in estrogen (Arcangelo and Peterson, 2013). The most common symptoms of estrogen deficiency are vasomotor symptoms, such as hot flushes and night sweats, and psychological and urogenital symptoms (Holloway, 2010). There are longer-term problems associated with estrogen deficiency such as osteoporosis and CVD (Holloway, 2010). Benefits and limitations should be discussed in detail with patients prior to starting HRT. A benefit of HRT includes relief from vasomotor symptoms such as relief from vaginal dryness, pain with sex, urinary frequency with either local or systemic hormone replacement therapy (HRT). Low-dose vaginal estrogen and ospemifene may provide effective therapy for the genitourinary syndrome (Stuenkel et. al., 2015). Other benefits of HRT consist of reduces or
stops recurrent urinary tract infections by locally applied HRT; reduces the risk of spine and hip fractures and combined HRT reduces the risk of colorectal cancer (Holloway, 2010, p. 500).
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