Pathogens+ disinfection F07 ESM 219

Pathogens+ disinfection F07 ESM 219 - ESM 219 F07 Pathogens...

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1 ESM 219 F07 Pathogens in the environment, Disinfection (NRC. 2001. Under the Weather: Climate, Ecosystems, and Infectious Disease) Pathogens in the Environment:animal transmitted • Rhabdovirus (Rabies RNA virus) – Infects entral nervous system – In saliva of infected animals • Hantavirus – Pulmonary infection (lung) – In feces of rodents Pathogens in the Environment • Rickettsias – Intracellular bacteria, infect fleas, lice, ticks • Rocky Mountain Spotted Fever, Typhus, other…. – Not cultured, but sequenced • Genome similar to human mitochondria – Small genome 1.1 Mbp – Few genes for independent metabolism and biosynthesis • Virulence genes similar to plant pathogen: Agrobacterium tumefaciens Pathogens in the Environment Borrelia burgdorferi – Spirochete, causes Lyme disease – Tickborne – Can treat with antibiotics (early) – Can be chronic Malaria Caused by protozoa in Sporozoa group Plasmodium vivax Plasmodium falciparum Infects 100 million people annually, kills 1 million Humans are mammal reservoirs Transmitted by mosquitos
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2 Pathogens in the Environment • West Nile virus: emerging,spread by mosquito from birds Yersinia pestis (Plague; gram-, facultative aerobe); rats are primary host; fleas are vectors • Pathogenic fungi: 50 known to cause human disease Clostridium tetani (endotoxin causes tetanus); ubiquitous anaerobic rod in soil Pathogens and Climate (NRC. 2001. Under the Weather: Climate, Ecosystems, and Infectious Disease)
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Pathogens+ disinfection F07 ESM 219 - ESM 219 F07 Pathogens...

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