The Case of the Sweaty Salesman Case Study - The Case of...

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The Case of the Sweaty Salesman Case Study #3 1.Define the bold terms in the text. 2. Thyroid hormones exert their effects on cells in a manner similar to steroid hormones; describe the mechanism of action of thyroid hormones. Thyroid hormones diffuse through the plasma membrane of a target cell and enter the nucleus of the cell. Once in the nucleus, the thyroid hormone binds to a specific receptor for the hormone located in the nucleus, forming a thyroid hormone-receptor complex. This complex then binds to a specific region of DNA known as responsive element. These responsive elements are unique for the different hormone-receptor complexes that can form. Binding of the thyroid hormone-receptor complex to the responsive element results in an increase in transcription of specific genes. The increase in gene transcription results in an

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