TOPIC 13 - TOPIC 13: CHEMISTRY OF DNA relevant reading and...

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TOPIC 13: CHEMISTRY OF DNA relevant reading and study on pp. 53 - 60, 510 - 523, 533 - 540 There is a single molecule of DNA in each chromosome. (in eukaryotes there is also much associated protein) The DNA molecule consists of two complimentary polynucleotide chains joined together by hydrogen bonds and twisted into a double helix. Each polynucleotide chain is a polymer of nucleotides. To understand how a complex macromolecule works — whether it be a protein, a polysaccharide, a lipid, or a nucleic acid — you must understand how that molecule is constructed. As much as 98 percent of human DNA does not code for a specific product. 'The Central Dogma' of molecular biology says that the genetic information in an organism's genes determines what an organism will be like and not vice versa. In essence then, it is a statement of the direction of flow of genetic information . Genetic information is encoded in DNA, it is transmitted by producing more DNA by a process called replication , or produces RNA by transcription , and the resulting RNA then produces proteins by a process called translation . You will be expected to learn the basic character of each of these processes in detail. But to do so you must first understand the chemistry of
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TOPIC 13 - TOPIC 13: CHEMISTRY OF DNA relevant reading and...

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