{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

TOPIC 19 - TOPIC 19 Protein Sorting and The Secretory...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
TOPIC 19: Protein Sorting and The Secretory Pathway The material is covered in the text on pp. 702 -712; 348 - 352 - but some related material will be scattered around in other parts of the text. The biosynthetic secretory pathway leads outward from the ER to the Golgi to the plasma membrane and other various organelles. Know exocytosis, lysosomes, early and late endosomes, M6P, constitutive vs. regulated secretion, endocytosis, bulk phase endocytosis (i.e., pinocytosis), phagocytosis, receptor mediated endocytosis, coated vesicles, clathrin coated, COPI (from ERGIC to ER), COPII (from ER to ERGIC), coated pits (clathrin). Guiding vesicular transport: SNAREs: v-SNARE, t-SNARE, endocytic vesicles, triskelion, adapter proteins, clathrin-coated vesicles, KDEL receptors, mannose 6-phosphate (M6P) receptors. Note that the glycosylation (usually starts in the ER but that the oligosacchride is modified in the Golgi complex. Exocytosis. Read section on lysosomes and know what these organelles do. Membranous bags of hydrolytic enzymes (acid hydrolases) with an
Image of page 1
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern