syllabus_2008 - Zoology 470 ~ Introduction to Animal...

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Zoology 470 ~ Introduction to Animal Development Spring, 2008 MWF, 1:20 pm, 132 Noland Hall c Instructor Jeff Hardin, Professor, Department of Zoology 327 Zoology Research, phone 262-9634 email: [email protected] [Note : NOT [email protected]!!] Office Hours: MF 2:25-3:15 pm, or by appointment Teaching Assistant Allison Lynch, Graduate Student, Genetics 319 Zoology Research, phone 265-2520 email: [email protected] Office Hours: appointment optional discussion: W 2:25 pm, room 342 Noland Required Materials Texts : S. Gilbert, Developmental Biology , 8th ed. Sinauer and Associates, 2006. Gilbert et al, Bioethics and the New Embryology . Sinauer and Associates, 2005. Required Additional Materials: Lecture handouts and additional readings will be available online, and will be announced in class and via email. What’s this course all about? Unifying Concepts Zoo 470 is designed to provide an overview of the major features of early embryonic development in animals, and the mechanisms that underlie them. We’ll focus on several major aspects of developmental biology: (1) How do developmental biologists think about embryos? We'll look at major big ideas in developmental biology, and how they guide modern experimental approaches to studying development. In many cases, classic experiments define the major problems being attacked at the molecular level today. (2) How do developmental biologists study embryos? We’ll look at molecular and cellular techniques that developmental biologists use, as well as basic properties of cells that we’ll need to know for the rest of the semester. (3) How do genes control development? We’ll look at how the regulation of specific genes influences the ways in which parts of the embryo become different. We’ll look at how are specific genes are turned “on” and “off” in different parts of an embryo, and why that’s important for building an embryo. (4) How does an animal embryo arise from a fertilized egg? We’ll look at how sperm and egg are produced, how they unite, and what the consequences are for the onset of embryonic development. We’ll look at how the basic body plan established, and how the basic organization of the embryo arises from the fertilized egg. In addition, we’ll look at the cellular mechanisms underlying morphogenesis, or “body building”. We’ll look at several well-studied invertebrate model systems to help us understand the molecular controls underlying pattern formation, including nematodes and fruit flies. We'll study gastrulation: how the primary axes of the body are constructed.
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syllabus_2008 - Zoology 470 ~ Introduction to Animal...

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