04-16-08 - Macromolecules biochemistry applies to...

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4/16/08 Macromolecules - biochemistry applies to everything and even though details may differ slightly – overall metabolism is universal to all living organisms Carbohydrates - monomer glucose - polymer starch strings of glucose covalently joined o glucose joins another glucose by loss of H 2 O – condensation - carbohydrates are hydrophilic – interact non-covalently with water - Hydrolysis o polymer + H 2 O monomer Lipids - basic structure fatty acid - usual form is a triglyceride - glycerol is metabolically derived from glucose Amino Acids - there are 20 different amino acids - have very diverse functions o ex) structural – collagen o catalysts – enzymes – recognition, antibodies, etc. Stability - concentrations of various components are kept within narrow limits o ex) concentration of glucose in blood is about 5mM (~900 mg/L) ingestion of glucose source causes rise but glucose is removed and metabolized in cells
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Membranes - membranes are barriers - molecules such as glucose can freely (but slowly) diffuse - membrane is hydrophobic o needs facilitators (proteins) in membrane that can increase rate of diffusion
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04-16-08 - Macromolecules biochemistry applies to...

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