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Unformatted text preview: 472 Pathology for the Health Professions Fl Cliomas Hyperﬂexion injury of spinal Neuroﬁbroma
Global ischemia of the brain cord Olj odendro liorna
Hematomas, epidural Int-racerebral hemorrhages Par inson’s 'sease
Hematomas, subarachnoid Medullohlastoma Ps chosis
Heniatomas, subdural Meningioma Sc wannoma
Huntington’s disease Menin 'tis Stroke '5
Hyperextension injury of spinal Multip e sclerosis Watershed (brain) infarct I cord Neurodegenerative disorders Wernicke-Korsakoff syndrome" l
After reading this chapter, the student should be able to:
“‘ 1. Describe the basic anatomy of the nervous system.
1‘ 2. Describe the morphology and function of the principal cells of the nervous system: neurons, astroglia, oligo— .Ir
dendroglia, rnicroglia, and ependymal cells. _/--
3. Ljstdthe principal functions of the cerebral cortex, basal ganglia, pons, medulla oblongata, cerebellum. and spinal Fi‘
cor . 4. Describe the pathogenesis of dysraphic malformations of the central nervous system and list three typical lesions. I """ 5. Describe the main cerebrospinal lesions caused by trauma.
‘5‘ 6. Compare epidural, subarachnoid, and subdural hematoma.
\ 7. Discuss the causes and pathology of cerebrovascular accidents (strokes).
8. Describe the circulation of the cerebrospinal ﬂuid and the pathogenesis of hydrocephalus. a“
9. Describe the route of infections of the central nervous system and the pathology of meningitis, encephalitis, and m.
cerebral abscess. d1
10. Describe the main neuropathologtc features of acquired immunodeﬁmency—related encephalopathy m
\l 1. (Diesel-Erie multiple sclerosns, discuss its pathogenesis, and describe the pnnmpal neuropathologic ﬁndings of this “,
‘12. Deseribe the neuropathology of alcoholism. “E
13. Deﬁne Alzheirner’s disease, describe the main pathologic ﬁndings in the brain, and correlate these with the clin- .
ical symptoms of this disease. fr-
“ 14. Describe the pathology of Parkinson‘s disease and Huntington‘s disease and correlate the pathologic ﬁndings fl
with typical symptoms. ﬁ'
15. List the ﬁve most common brain tumors and describe their pathologic and clinical features II-
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k 32. Review Questions List the main components of the central and peripheral nervous systems. Describe. the functions of the. four major lobes of the brain. Compare the functions of the Iniril'nr'ain. polls. and ntmlulla ohlollgata with that of the cerebellum.
Deseribe. the. function of the spinal cord. Describe the circulation of the eerebrospinal fluid. List the main cells of the nervous system. \‘i-"bat
What List the. main elysraphit‘ disorders of the ventral nervous systetn and tlest-ril'te their pathogenesis. are "It? "105T lIIIJJOITBI'II ditiﬂilﬁﬂf-‘I (If [i]? nervous hiyh‘l'ﬂl'll? art- the sites of brain herniation eausetl by intl‘at't'anial hypertension? List the most important int'ral'ranial hemorrhages atnl Llest-ril'te their causes. \Vhat stroke? W’hat is global cerebral ESL-hernia. and what are its ("t'lnst'tfut’llt‘t'ﬁts? \Vbat is the pathogenesis of “watershed infarets" and laminar net'rosis of the brain?
Deserihe the pathology of eerehral infarcts. Correlate the pathology of intraeerel'tral hemorrhage with the (‘linieal Features of this disease.
What are the main pathologitr ﬁndings following brain injury? (Jotnpare ltyperexlension anal hyperflexion injuries of the cervical spine. Compare barterial and viral infections of the eentral nervous system. What are. prions? List the most important protozoa! and fungal causes of opportunistit- diseases ol' the central nervous
Compare the pathology of encephalitis anrl meningitis. Describe the “natures of neurosyphilis. ‘\" What are the most important AIDS—related central nervous system lesions ‘Wiaat is multiple selerusis? system. Correlate the palhologit' features of ntultiple selenlsis with the elini ‘all signs and syntptt'uns of this disease. How rlo inborn errors of nletabolistn after! the central nervous systent? W’hat is the eaIISe and what are the signs of W'erniel-te-Korsakoft' syntlrmne? How does aleobol affect the brain? What are the [Host important neonJtlegenerative diseases? W’hat is Alzlleinler‘s tilisease. and bow is it tliagnosetl? Desc'l'ibe the tnat't'oseupit' and tnitrroseotitit' pathologie lintlings in Alzheimer‘s disease. “"113! is Parkinson's disease? ...
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- Fall '08