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Lec6_7_07

Lec6_7_07 - Lec6&7 2007 INTRODUCTORY ANIMAL PHYSIOLOGY...

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INTRODUCTORY ANIMAL PHYSIOLOGY BIOAP 311/VETBM 346 FALL 2007 Ion Gradients and Membrane Potentials (Readings - Chapter 2, Lecture notes) I. Major Topics/Concepts to be covered: 1. Ion gradients and the forces determining equilibrium. 2. The Nernst Equation. 3. The Donnan equilibrium. 4. The RESTING POTENTIAL and what factors determine it. 5. How cells establish and maintain transmembrane electrochemical potentials. 6. The Goldman Equation. 7. Responses of cells to changes in transmembrane electric potential. II. You will have learned the material when you can: 1. Explain and graph the temporal changes in transmembrane potential to a step change in externally applied current. 2. Use the electrical terms applied to membranes with familiarity. 3. Predict what will happen to the resting potential when ion concentra- tions or permeabilities are changed (this will mean having a working understanding of the Nernst and Goldman equations). III. Sample Problems: 1. What will happen to the distribution of ions across the cell membrane of a normal cell if all active transport processes are suddenly poisoned? What about the membrane potential?
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Lec6_7_07 - Lec6&7 2007 INTRODUCTORY ANIMAL PHYSIOLOGY...

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