AMINO ACID METABOLISM - KAPLAN USMLE STEP 1

AMINO ACID METABOLISM - KAPLAN USMLE STEP 1 - pyruvate for...

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Carbamoyl-P Sy­ nthetase (CPS-I) deficiency Ornithine transc­ arbamoylase (OTC) deficiency Argininosuccinate synthetase defic­ iency Argininosuccinate lyase deficiency Arginase deficiency Maple Syrup Urine Disease strictly ketogenic AA both ketogenic + glucogenic AA strictly glucogenic AA
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7 metabolic intermediates d­ erived from AA AA that form pyruvate AA that form acetyl-CoA AA that form acetoacetyl-CoA AA that form oxaloacetate AA that form fumarate AA that form propionyl-CoA (then converted to succinyl-CoA) AA that form glutamate (then converted to alpha-ketoglutarate) propionic aciduria
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methylmalonic aciduria pyridoxal phosphate CPS-1 activation arginase found only in amino groups in muscle liver uses
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Unformatted text preview: pyruvate for liver uses amino groups for phenylketonuria (PKU) PKU Sx dihydrobiopterin reductase defici­ ency PKU Tx NutraSweet precursor for tyrosine sulfur for cysteine synthesis comes from if phenylalanine deficient in diet if methionine essential in diet elevated plasma homocysteine is risk factor for homocystinuria causes of homocystinuria homocystine cysthathionuria Parkinson dz: cause Parkinson preva­ lence Parkinson Sx Parkinson Tx Carbidopa carcinoid tumors nitroglycerin and other angina tx porphyria lead poisoning and heme synthesis 4 broad causes of hyperbilirubin­ emia anabolism catabolism...
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This note was uploaded on 08/23/2008 for the course MS 1 taught by Professor Fall2008 during the Fall '08 term at Nova Southeastern University.

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AMINO ACID METABOLISM - KAPLAN USMLE STEP 1 - pyruvate for...

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