Midterm 1 example

Midterm 1 example - Name: BMEN 689 Mechanical Regulation of...

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Name: . BMEN 689 Mechanical Regulation of Cell Signaling Midterm #1 Practice Carefully read each question. There are 100 points total on the exam. Problems 1-11. Multiple choice – there is only one correct answer (4 pts each). 1. An enzyme changes which of the following aspects of a reaction: A. equilibrium ratio of product to reactant B. rate of the reaction C. structure of the product D. thermodynamics of the reaction E. all of the above 2. Covalent bonds between which of the following pairs of atoms are nonpolar? A. C-C B. C-H C. O-H D. A and B E. B and C 3. Which of the following amino acid monomers has a net negative charge? A. Lysine at pH = 12 B. Aspartate at pH = 5 C. Glutamine at pH = 6 D. A and B only E. none of the above 4. Two-dimensional (2-D) gel electrophoresis performed under denaturing conditions can be used to separate proteins according to which of the following conditions? First Dimension Second Dimension A. Subunit molecular weight Density B. Density Subunit molecular weight C. Amino acid composition Charge D. Isoelectric point (pI) Subunit molecular weight E. Hydrophobicity Isoelectric point (pI) 5. Secondary structures are stabilized primarily by: A. Disulfide bonds on adjacent cysteine amino acids B. Hydrophobic interactions C. Hydrogen bonding between backbone oxygen and hydrogen atoms 1
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1 C S 1 V 0 without inhibitor with inhibitor Name: . D. B and C only E. all of the above 6. Based on the graph, the inhibitor A. increases V max , but doesn’t change K M B. decreases V max , but doesn’t change K M C. increases K M , but doesn’t change V max D. decreases K M , but doesn’t change V max E. increases V max and decreases K M 7. If the equilibrium constant for the reaction A+B C is 0.25 and the initial concentration are [A] = 25 mM, [B] = 4 mM and [C] = 25 mM, then the reaction: A. will proceed in the direction it is written, producing a net increase in the concentration of C B. will require energy, which can be derived from ATP hydrolysis C. will proceed in the reverse direction, producing a net increase in the concentration of A D. is at equilibrium E. none of the above 8. Hydrolysis of ATP: A. is endothermic B. has a positive ΔG value C. must be coupled to an energetically favorable reaction D. all of the above E. none of the above 9. Which of the following would contribute to increasing the probability that two DNA strands will separated? A. Decreasing temperature below body temperature (37°C)
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This note was uploaded on 08/30/2008 for the course BMEN 289 taught by Professor Kaunas during the Spring '07 term at Texas A&M.

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Midterm 1 example - Name: BMEN 689 Mechanical Regulation of...

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