PSYCH 470 - Risperidone - [Redacted 1 Pharmacological...

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[Redacted] 1 Pharmacological Profile and Studies of Risperidone [Redacted] Penn State University Atypical antipsychotics are a recent advance in the treatment of psychological disorders; they have only been around since the introduction of clozapine in 1989 (Rivas-Vazquez, Blais, Rey, & Rivas-Vazquez, 2000). Risperidone, introduced in 1994, has been particularly effective in the treatment of schizophrenia, which it is primarily used to treat, and also bipolar mania, and autistic disorder (Janssen, 2006). Studies have shown that while risperidone has less adverse side effects than the older, conventional antipsychotics (Rivas-Vazquez et al., 2000), there has been evidence that there is an increased mortality rate in the elderly (MD Consult, 2005), and prevalence of tardive dyskinesia (Janssen, 2006). Risperidone is an atypical antipsychotic, the word atypical referring to the reduction of adverse side effects with increased efficacy in reducing the negative symptoms of schizophrenia (Rivas-Vazquez et al., 2000). In developing a treatment for such psychological disorders as schizophrenia, it is important for a drug such as risperidone to selectively block the overproduction of certain chemicals in the brain, such as serotonin and dopamine.
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