Exam3 Key - Page 1 of 6 Systems Neuroscience Exam 3...

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Page 1 of 6 Systems Neuroscience Name: _________________________________________ Exam 3, practice The exam is closed book, closed notes, no calculators, no talking, etc. There is a fresh copy of the “Exam3_referenceSheet.pdf” stapled to the back of the exam. You may remove that sheet and use it for added notes and reference. NO CREDIT WILL BE GIVEN FOR ANYTHING WRITTEN ON THE REFERENCE SHEET 1) (27 points total) You have just identified a new area of the thalamus, called the rostral ventral nucleus (RVM). You believe that RVM is a higher-order thalamic nucleus for the auditory system that connects with A1 and A2 in analogous ways to the connections POm makes with S1 and S2. a) Draw below the patterns of connections to and from RVM that you would expect to find between it and A1 and A2. Do not include MVN or the connections made from MVN in the diagram, but **do** include connections within layers A1 and within layers of A2 and any direct connections between A1 and A2. (9 points)
Page 2 of 6 b) To further test your hypothesis that RVM is a higher-order thalamic nucleus, you decide to read up on research done on higher-order nuclei in somatosensory systems. The first study you find is "Properties of the thalamic projection from the posterior medial nucleus to primary and secondary somatosensory cortices in the mouse" by Viaene, Petrof, and Sherman. Based on this study, make a hypothesis about how the RVM inputs to A1 vs. the RVM inputs to A2 will behave. Then, propose an experiment to test your hypothesis (including manipulation(s), measurement(s), expected results, and explicit discussion of the relationship between expected results and your hypothesis). (9 points)

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