{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Lecture 5 bacterial flagella - BME 418 Quantitative Cell...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
BME 418, Quantitative Cell Biology Alan J. Hunt Lecture #5: bacterial flagella, motility Bacterial Flagella: we've discussed how energy can be stored in a chemical or electrochemical gradient across a membrane, and in the example of lactose symport how this energy can be harnessed by a cell to perform useful work. What other sort of work can be accomplished in this way? In fact many things: a particularly striking example of how sophisticated this can become is the bacterial flagella, which allow bacteria to undergo movements that are much quicker and more controlled than diffusion. E. coli. only grow flagella in a nutrient starved environment (chemotaxis). Other taxis responses include: - Phototaxis - Aerotaxis - Magnetotaxis Components of flagellar structure are well established from biochemistry and molecular genetics: - make a mutant that has a motility failure - look for missing components of flagellar structure (light, EM) - use genetics to identify mutant sequence Flagella: - rigid helical rod - consist of one protein: flagellin At the base of flagella a hook inserts into the basal body. This structure rotates in the membrane. All components have been identified, but their function is still being worked out. Construction is accomplished by hierarchical operon induction. Bacteria can operate this way because bacterial mRNA can encode for more than one protein.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern