lecture15 - OBJECTIVES Modeling and remodeling of bone...

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Unformatted text preview: OBJECTIVES Modeling and remodeling of bone Age-related bone loss and repair Mechanical testing of bone. Modeling & Remodeling of Bone Stages in life of bone Involve three fundamental Processes Activation (A) Signals such as local damage/Death of osteocyte Resorption Osteoclasts take away or dissolve the damaged bone or bone with dead osteocytes Formation New bone formation by osteoblasts Why Model? Optimize shape and minimize resulting deformation To optimize bone Increase the size of the bone Change the shape of the bone Why Model? Increase the size of bone Osteoblast will form more bone Why Model? Change the shape of the bone Osteoclast will resorb bone and osteoblast will form bone But the order doesnt matter Why Model? Optimize shape and minimize resulting deformation Modeling Alteration in size or shape of bone by bone resorption and formation at different surfaces during growth Example Why Model?Why Model?...
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This note was uploaded on 09/07/2008 for the course BMED 4540 taught by Professor Vashishth during the Fall '07 term at Rensselaer Polytechnic Institute.

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lecture15 - OBJECTIVES Modeling and remodeling of bone...

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