Lecture Outline 3 - Cell Metabolism- Lecture Outline 3...

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Cell Metabolism- Lecture Outline 3 Theme: Cell Metabolism Silverthorn text reference is Chapter 4 and Appendix C (B with 3 rd Ed.) Learning Objectives: 4-1. Define cellular work and explain the types observed. 4-2 Explain the Laws of Thermodynamics and describe how energy is transferred throughout the environment. 4-3. Explain the necessity of using enzymes to control metabolism and the cost of this strategy 4-4. Identify and Describe the biological fuels by their specific catabolic pathways 4-5. Compare and Contrast the energy yield from both anaerobic and aerobic ATP synthesis pathways for each biofuel 4-6. Describe the pathways of energy storage by the biological fuel molecules and explain why all excessive fuel is stored as fat Appendix-7. Describe the DNA replication strategy and explain the benefit of it Appendix-8. Define a Gene and explain how the information is stored and accessed 4-9. Sequentially order and describe the events of Transcription and Translation to explain the pathway of protein synthesis. Key terminology: Reaction, Reaction Rate, Energy, Activation energy, Free energy change, Equilibrium, Affinity, Specificity Endergonic, Exergonic, forward reaction backward reaction, Bidirectional reaction, products, reactants, Biological fuel, Kreb's, Glycolysis, Chemiosmotic theory, oxidative / phosphorylation reaction, Catabolic, Anabolic, all molecule names should be recognizable, Kinetic energy, Potential energy, modulation, work, Enzyme, Proenzyme, Cofactor, Coenzyme, I. Cellular Metabolism – All Chemical WORK of the cell A. Work – Ability to utilize Energy; kinetic (used for work 60%) + heat (goes back into universe 40%); able to be inefficient because we have abundant energy supply (supply and demand) 1. Application of Energy- sun is largest energy source transferred to plants animals humans energy forms: radiation, biological, mechanical, heat a. Laws of Thermodynamics: 1. All Energy in the Universe is Constant (can neither be created or destroyed) 2. All energy is moving toward heat (lowest source of energy product) b. Applying the Laws of thermodynamics – Energy Transfer Potential Energy- energy stored in masses (moving toward heat/low energy status, which gives off kinetic energy that can be used) Activation Energy- “push” needed to start a reaction Kinetic Energy- energy that can be used for work
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2. Types of Cellular Work Observed a. Chemical- signal to begin cell replication cycle; interphase and mitosis/cytokinesis apoptosis- programmed cell death b. Transport- work within a cell or between cells
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Lecture Outline 3 - Cell Metabolism- Lecture Outline 3...

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