Bacteria Review Sheet - www.medfools.com 1 Medfools...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: www.medfools.com 1 Medfools Bacteriology a la chart for the USMLE I Adapted from notes from UCLA., with additional corny mnemonics Staphylococcus aureus ( virulent ) (nonmotile, nonsporeforming, facultative anaerobe) Gm+ cocci Diseases Characteristics Habitat/Transmission Pathogenesis Diagnosis Treatment Prevention *Skin infections: impetigo, cellulitis, erysipelas, abcess, furuncle, carbuncle *Bacteremia/sepsis: hematogenous spread *Acute endocarditis: DESTRUCTIVE (compare to S. viridans and S. faecalis ) *Pneumonia damaging process, cavitations, empyema, effusions *Osteomyelitis/septic arthritis- hematogenous and traumatic spread *Food poisoning 1-8 hr onset, vomiting, preformed toxin *Tox shock syndrome- fever, vomiting, diarrhea, diffuse erythematous rash Gm + cocci in grapes/clusters Catalase + coagulase + Ubiquitous in environment; normal flora of skin/nose Spread through lesions, fomites Enterotoxin- vomiting, diarrhea, heat resistant, (actually released in gut) TSST-1 tampon use, wounds, superantigen Exfoliatin- scalded skin TISSUE SPREAD: Alpha toxin (lechthinase)- skin necrosis;hemolysis Hyaluronidase- degrades proteoglycans Fibrinolysin- lysis fibrin clots IMMUNE EVASION: Protein A- binds IgG-Fc, blocks opsonization and complement fixation Coagulase- activates prothrombin Hemolysin- destroys RBCs, PMNs, M0s, platelets Leukocidin- destroys WBCs Gm + cocci in grapes, Catalase differentiates from Strep. S. aureus: Beta hemolysis, coagulase, Yellow (Au) pigment (coagulase causes coagulation! ) Coagulase neg: S. epidermidis: novobiocin sensitive sensitive skin S. saprophyticus: Novobiocin resistant Beta lactamase production is common! Use methicillin, nafcillin, dicloxacillin MRSA- vancomycin none S. epidermitis: associated w/ IV catheters, damaged/prosthetic heart valves: INSIDIOUS onset, Nosocomial, LESS virulent . Blood culture Contaminant S. saprophyticus: Community acquired UTI in young women www.medfools.com 2 Streptococcus viridans ( GABHS ) (nonmotile, nonsporeforming) Gm+ cocci Diseases Characteristics Habitat/Transmission Pathogenesis Diagnosis Treatment Prevention *Pharyngitis- strep throat, erythema, tonsillar exudate, fever *Skin/soft tissue infections- impetigo, cellulitis, necrotizing fascitis *Scarlet fever- centrifugal, red rash, erythrogenic toxin, slap cheek, strawberry tongue *Tox shock syndrome- clinically like Staph TSS *Rheumatic fcver- fever, myocarditis, polyarthritis, chorea, subcutaneous nodules, erythema marginatum rash. Mitral valve disease follows pharyngitis, NOT skin infections. Abs vs. bacteria cross react w/ joint and heart antigens *Acute GN- hypertension, hematuria, edema of face/ankles....
View Full Document

This note was uploaded on 06/17/2008 for the course MOD 2 taught by Professor Cunningham during the Spring '08 term at University of North Texas Health Science Center.

Page1 / 13

Bacteria Review Sheet - www.medfools.com 1 Medfools...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online