Biochem Exam 1 key - Biochemistry 415/515 2008 January 29,...

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Biochemistry 415/515 2008 Name ________________________ January 29, 2008 uniqname________________________ Biochemistry 415/515 Exam 1 of 4 100 points total Instructions: 1. Please put your name on each page of the exam, your uniqname on the first page and fill out the scantron sheet with your student ID number, name and uniqname. 2. First, read through the exam. Answer the immediately obvious questions when you can. Put a question mark by the ones you’re not sure about. . 3. Raise your hand to ask questions. It is possible that you may be focusing on a phrase that can be stated differently. 4. If you are still here after 60 minutes, get up and walk around for 2 minutes. Then start doing the test from back to front. Section A. Multiple choice (84 points-2 points per question). Choose the most appropriate answer. 1. In general terms, which of the following is true of all DNA double helices: (a) The sequence of bases within all DNA helices is the same (b) The monomers are joined together by phosphodiester bonds (c) The GC base pair has the same number of hydrogen bonds as the an AT base pair (d) a and b above (e) a, b and c above 2. Which of the following amino acids has a side chain capable of forming an electrostatic bond with glutamate? (a) valine (b) lysine (c) glycine (d) glutamine 3. Hydrogen bonds in biological systems involve which atoms to act as donors and acceptors? a. carbon, nitrogen b. oxygen, carbon, nitrogen c. oxygen, nitrogen d. carbon, oxygen Midterm Examination #1 Page 1
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Biochemistry 415/515 2008 Name ________________________ January 29, 2008 uniqname________________________ 4. Which of the following is correct about alpha helices? a. They can be asymmetric with respect to polarity. b. They are not accounted for by a Ramachandran plot c. They are the tertiary structure of a protein. d. The amino acid side chains are on the inside of the helix. 5. The absorbance of proteins between 270-290 nm is due to the following amino acids except a. Histidine b. Tryptophan c. Tyrosine d. Phenylalanine 6. One piece of evidence to support the idea that the peptide bond is planar is: a. peptide bonds always occur between alanine and glutamate residues b. the C-N bond distance is shorter than would be expected for a single bond c. the carbonyl oxygen is reduced by β -mercaptoethanol d. the carbonyl oxygen is oxidized by β -mercaptoethanol 7. An amino acid found in a protein is shown below. What is this amino acid? a. cysteine b. cystine c. histidine d. proline Midterm Examination #1 Page 2
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Biochemistry 415/515 2008 Name ________________________ January 29, 2008 uniqname________________________ 8. At a pH of 7.0, the amino acid side chain of this amino acid in question 7 is approximately: (a) 90% negatively charged (b) 10% positively charged (c) 50% negatively charged (d) 0% negatively charged 9. The dielectric constant of hexane is less than the dielectric constant of ethanol. This means that: a.
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This note was uploaded on 09/11/2008 for the course BIOLCHEM 415 taught by Professor Michaeluhler during the Spring '06 term at University of Michigan.

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Biochem Exam 1 key - Biochemistry 415/515 2008 January 29,...

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