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hw4key - ,Sept.2 1 . . chromosomesf

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Genetics Homework 4 – due in lecture Tuesday, Sept. 2 1. Six evolutionarily related but separate species each arose through a single inversion in a chromosome of its predecessor. The progenitor species had the chromosomal composition of ABCDEFGH. The following represent the chromosomes from the related species (not in order of how they arose): (1) AEBGHDFC (2) AEDHGFBC (3) AEBGFDHC (4) AEDCBFGH (5) AEDHGBFC Show how the 5 species arose from the original progenitor by indicating where the inversions occurred. A BCDE FGH AED CBFGH AEDHG FB C AE DHGB FC AEBG HDF C AEBGFDHC 2. Wild-type phage T4 grows on both E. coli B and E. coli K12( λ ), producing turbid plaques. The rII mutants of T4 grow on E. coli B, producing clear plaques, but do not grow on E. coli K12( λ ). This host range property permits the detection of a very low number of r + phages among a large number of rII phages. With such a sensitive system, it is possible to determine the genetic distance between two mutations within the same gene – in this case, the rII locus. Suppose E. coli B is
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