testtwo mibo 6700

testtwo mibo 6700 - Aspergillus: produces aflatoxins which...

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: produces aflatoxins which can be found in food/grains in storage…cause chronic liver toxicity and possibly cancer through effects on hepatocytes -comiting, abdominal pain, hepatitis, and death Claviceps : produces ergots in grain storage areas; moldy rye grain Saint Anthony’s Fire: C. purpurea—skin was on fire before necrosis -causes vasoconstriction and intestinal problems -used to treat epilepsy, migraines (tartrate), or induce labor (ergometrine) and/or hallucinations…LSD Gangrenous Ergotism: cold/prickly swollen burning numbness -known as dry gangrene Convulsive ergotsm: CNS affected; itnching, numbness, cramps then sustained convulsions Fusarium : produce fumonisins in corn contamination -a carcinogen, birth defects and neurotoxin -sphingolipid action Stachybotrys : produce trichothecenes -affects alimentary canal: hemorrhage, Mycetismus Choleriformis Group I -cell destruction, liver and kidney damage; onset of symptoms 6-10 hours -caused by Amanita and some Galerina - A. phalloides is deathcap mushoom (greenish metallic top) -produce phallotoxins and amatoxins; most important— alpha and beta-amanitin -cyclic octapeptides that inhibit RNA polymerase II -initially stage of cramps and vomiting then remission -return with hepatic and renal damage phase -thioctic acid has some effect Mycetismus Sanguinarius Group II -cell destruction, liver and kidney damage; onset of symptoms 6-10 hours -caused by Gyromitra - monomethylhydrazine and its derivatives cause effects on CNS and delayed hepatotoxicity - pyridoxine and sodium phenoarbital have been used effectively, as has thioctic acid Group III - -mostly ANS; symptoms arise 20 min-2 hours Coprinus causes violent vomiting and nausea when combined with alcohol Mycetismus Nervosus Group IV- mostly ANS; symptoms arise 20 min-2 hours -mostly Inocybe and Clitocybe -produce muscarine which affects receptors in PSNS -headache, nausea, vomiting, sweating -treated with atropine (contraindicated when caused by A. Muscaria) Group V - central nervous system effects; arise 20 min to 2 hours later - ibotenic acid-muscimol
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testtwo mibo 6700 - Aspergillus: produces aflatoxins which...

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