CAD Concept Map - Diagnostics Labs 1 Lipid profile(<200 cholesterol or <150 triglycerides >40 HDL 2 Fasting blood glucose 3 ECHO Stress testing

CAD Concept Map - Diagnostics Labs 1 Lipid profile(<200...

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Worsening of Clinical Manifestations/Complications Unstable angina (UA) and myocardial infarction (MI) are more serious manifestations of CAD and are termed acute coronary syndrome (ACS) CAD(->Angina) Atherosclerosis is major cause. It is the deposit of cholesterol and lipids within the intimal wall of artery Progressive disease that develops in stages. 1. Fatty streak 2. Fibrous plaque 3. Complicated lesion Diagnostics, Labs 1. Lipid profile (<200 cholesterol or <150 triglycerides, >40 HDL) 2. Fasting blood glucose 3. ECHO, Stress testing & pharmacologic nuclear testing Chronic Stable Angina Diagnostics/Labs 1. Chest xray: cardiac enlargement, aortic calcifications, & pulmonary congestion 2. 12 Lead ECG 3. Lipids serum & ECHO to confirm CAD and identify spefic risk factors for CAD 4. Cardiac catherization & coronary angiography: if significant amount of myocardium is ischemic under stress Clinical Manifestations Xanthomas: fatty deposit under the surface of skin Normally some arterial anastomoses or connections, termed collateral circulation, exist within the coronary circulation. Their growth and extent is attributed to the inherited predisposition to develop new blood vessels and the presence of chronic ischemia. Patients may be asymptomatic for years or may develop chronic stable chest pain CAD Drug Therapy “statin”- works on liver to ↓ release of cholesterol and ↑HDL and ↑removal of LDL, a. Liver breakdown: monitor liver enzymes b.

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