100%(14)14 out of 14 people found this document helpful
This preview shows page 1 out of 1 page.
Worsening of Clinical Manifestations/ComplicationsUnstable angina (UA) and myocardial infarction (MI) are more serious manifestations of CAD and are termed acute coronary syndrome(ACS)CAD(->Angina)Atherosclerosis is major cause. It is the deposit of cholesterol andlipids within the intimal wall of arteryProgressive disease that develops in stages. 1.Fatty streak2.Fibrous plaque3.Complicated lesionDiagnostics, Labs1.Lipid profile (<200 cholesterol or <150 triglycerides, >40 HDL)2.Fasting blood glucose3.ECHO, Stress testing & pharmacologic nuclear testingChronic Stable Angina Diagnostics/Labs1.Chest xray: cardiac enlargement, aortic calcifications, & pulmonary congestion2.12 Lead ECG 3.Lipids serum & ECHO to confirm CAD and identify spefic risk factors for CAD4.Cardiac catherization & coronary angiography: if significant amount of myocardium is ischemic under stressClinical ManifestationsXanthomas: fatty deposit under the surface of skinNormally some arterial anastomoses or connections, termed collateral circulation, exist within the coronary circulation. Their growth and extent is attributed to the inherited predisposition to develop new blood vessels and the presence of chronic ischemia.Patients may be asymptomatic for years or may develop chronic stable chestpainCAD Drug Therapy“statin”- works on liver to ↓ release of cholesterol and ↑HDL and ↑removal of LDL,a.Liver breakdown: monitor liver enzymesb.