Worksheet 12_gene reg_Spr17

Worksheet 12_gene reg_Spr17 - Worksheet 12_Refer Learning...

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Worksheet 12_Refer chapters 16, 18 Learning Objectives: 1) Draw the lac operon and indicate location of promoter, operator, structural genes. Name structural genes and the corresponding proteins formed. 2) Explain positive and negative regulation of the lac operon. What is the role of cAMP and CAP? What is glucose effect? 3) Is Lac operon on/off in presence/absence of lactose? 4) Explain how the trp operon is organized and regulated 5) Describe the different levels of packaging of DNA in the nucleus. 6) What are histones? What are the different types of histones? What are nucleosomes? 7) What are different points of regulation of gene expression in Eukaryotes? 8) What is differential gene expression? 9) Explain the role of activators and repressors in gene expression. 10)What are proximal and distal control elements? 11)What is the role of general transcription factors? 12)What are enhancer sequences? How do they regulate gene expression? 13)Explain combinatorial control of gene expression with an example
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