Lec_4 - CHAPTER 3 PROTEINS I SHAPE AND STRUCTURE OF...

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CHAPTER 3 PROTEINS I. SHAPE AND STRUCTURE OF PROTEINS
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Components of a protein Figure 3-1 Molecular Biology of the Cell (© Garland Science 2008) 20 amino acids Backbone Side chain Names Types Joined by Peptide bonds Polypeptide = protein
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The Shape of a Protein Is Specified by Its Amino Acid Sequence Figure 3-4 Molecular Biology of the Cell Noncovalent bonds govern protein “folding” or protein “conformation” ? ? ?
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Amino acids Amino acids with similar side chain properties have similar function. Need to know all 20 amino acid names and properties, and be able to identify their side chains.
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Hydrophobic forces causes nonpolar amino acids to coalesce to the middle of the protein.
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Figure 3-3a Molecular Biology of the Cell (© Garland Science 2008) Steric collisions restrict the path of the polypeptide backbone.
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Figure 3-6a Molecular Biology of the Cell (© Garland Science 2008) Proteins fold to an energetically stable conformation.
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Describing the structure of a protein.
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